Compound as reactive (1)
testosterone + NAD(P)+ → androst-4-ene-3,17-dione + NAD(P)H + H+
Compound as product (1)
testosterone + NADP+ ← androst-4-ene-3,17-dione + NADPH + H+
Reversible reaction (3)
testosterone + NAD+ ↔ androst-4-ene-3,17-dione + NADH
17-β-hydroxy-5-α-androstan-3-one + NADP+ ↔ testosterone + NADPH + H+
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + testosterone + oxygen ↔ 2 an oxidized ferredoxin [iron-sulfur] cluster + H2O + 1α-hydroxytestosterone