Compound as reactive (2)

N¹-(5-phospho-β-D-ribosyl)glycinamide + formate + ATP → N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide + H⁺ + phosphate + ADP

5,10-methenyltetrahydrofolate mono-L-glutamate + N1-(5-phospho-β-D-ribosyl)glycinamide + H2O → N2-formyl-N1-(5-phospho-β-D-ribosyl)glycinamide + 2 H+ + 5,6,7,8-tetrahydrofolate

Compound as product (1)

5-phospho-β-D-ribosylamine + glycine + ATP → N¹-(5-phospho-β-D-ribosyl)glycinamide + H⁺ + phosphate + ADP

Reversible reaction (1)

N¹-(5-phospho-β-D-ribosyl)glycinamide + 10-formyl-tetrahydrofolate mono-L-glutamate ↔ N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide + H⁺ + 5,6,7,8-tetrahydrofolate