Compound as reactive (2)

2 an oxidized ferredoxin [iron-sulfur] cluster + H₂O + prenyl diphosphate ← 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H⁺ + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

2 an oxidized ferredoxin [iron-sulfur] cluster + H₂O + isopentenyl diphosphate ← 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H⁺ + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate

Compound as product (2)

2 an oxidized ferredoxin [iron-sulfur] cluster + H₂O + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate ← 2 a reduced ferredoxin [iron-sulfur] cluster + 2-C-methyl-D-erythritol-2,4-cyclodiphosphate + H⁺

2 H⁺ + (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate ← H₂O + isopentenyl diphosphate

Reversible reaction (1)

H₂O + isopentenyl diphosphate + NAD(P)+ ↔ (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H⁺