Compound as reactive (1)

H₂O + ADP-5-ethyl-4-methylthiazole-2-carboxylate → H⁺ + 4-methyl-5-(2-phosphooxyethyl)thiazole + AMP + CO₂

Compound as product (1)

glycine + NAD⁺ + hydrogen sulfide → 2 H⁺ + 3 H₂O + nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate

Reversible reaction (1)

glycine + NAD⁺ + L-cysteine ↔ nicotinamide + ADP-5-ethyl-4-methylthiazole-2-carboxylate