Compound as reactive (5)
2-chloro-2-hydroxyethyl-CoM ← coenzyme M + chlorooxirane
coenzyme M + N5-methyltetrahydromethanopterin → methyl-CoM + tetrahydromethanopterin
2-(R)-hydroxypropyl-CoM ← coenzyme M + (R)-1,2-epoxypropane
(2S)-2-hydroxypropyl-CoM ← coenzyme M + (S)-1,2-epoxypropane
2-hydroxyethyl-CoM ← coenzyme M + ethylene oxide
Compound as product (6)
coenzyme M + NADP+ + acetoacetate ← NADPH + 2-oxopropyl-CoM + CO2
malonate + coenzyme M + NADP+ ← NADPH + 2-carboxyethyl-CoM + CO2
H2O + sulfoethylcysteine → coenzyme M + pyruvate + ammonium
coenzyme M + methanophenazine + coenzyme B ← dihydromethanophenazine + CoB-CoM heterodisulfide
2 a reduced ferredoxin [iron-sulfur] cluster + 2 CO2 + coenzyme M + coenzyme B ← 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 formate + CoB-CoM heterodisulfide
2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + coenzyme M + coenzyme B ← 2 an oxidized ferredoxin [iron-sulfur] cluster + 2 H2 + CoB-CoM heterodisulfide
Reversible reaction (6)
tetrahydrosarcinapterin + methyl-CoM ↔ 5-methyl-tetrahydrosarcinapterin + coenzyme M
2 Na+ + coenzyme M + N5-methyltetrahydromethanopterin ↔ 2 Na+ + methyl-CoM + tetrahydromethanopterin
coenzyme M + coenzyme B + fumarate ↔ CoB-CoM heterodisulfide + succinate
coenzyme M + methanethiol ↔ methyl-CoM + H+ + HS-
2 an oxidized ferredoxin [iron-sulfur] cluster + coenzyme M + coenzyme B ↔ 2 a reduced ferredoxin [iron-sulfur] cluster + 2 H+ + CoB-CoM heterodisulfide
2 coenzyme M + methanol ↔ methyl-CoM + H2O