Compound as reactive (2)

2 H⁺ + menaquinol-8 + fumarate → menaquinone-8 + succinate

dimethyl sulfoxide + menaquinol-8 + H⁺ → H₂O + menaquinone-8 + dimethyl sulfide

Compound as product (3)

menaquinone-8 + formate → menaquinol-8 + CO₂

2 H⁺ + menaquinone-8 + (S)-malate → menaquinol-8 + oxaloacetate

S-adenosyl-L-methionine + demethylmenaquinol-8 → S-adenosyl-L-homocysteine + menaquinol-8 + H⁺

Reversible reaction (2)

an oxidized electron donor + menaquinol-8 ↔ menaquinone-8 + a reduced electron donor

menaquinol-8 + nitrate ↔ H₂O + menaquinone-8 + nitrite