Compound as reactive (3)

H₂O + di-trans,octa-cis-undecaprenyl diphosphate → H⁺ + phosphate + di-trans,octa-cis-undecaprenyl phosphate

di-trans,octa-cis-undecaprenyl diphosphate + core oligosaccharide-lipid A (E. coli K-12 core type) → lipid A-core 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate

α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A + di-trans,octa-cis-undecaprenyl diphosphate → α-D-Kdo-(2→4)-α-D-Kdo-(2→6)-lipid A 1-diphosphate + di-trans,octa-cis-undecaprenyl phosphate

Compound as product (17)

2 a peptidoglycan dimer (S. aureus) + 3 H₂O → 4 D-alanine + a peptidoglycan with D,D cross-link (S. aureus) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

2 ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → di-trans,octa-cis-undecaprenyl diphosphate + ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine

a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide → a mature peptidoglycan_(n) (meso-DAP containing) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

isopentenyl diphosphate + di-trans,poly-cis-decaprenyl diphosphate → 5 H⁺ + di-trans,octa-cis-undecaprenyl diphosphate + diphosphate

a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide → a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate) tripeptide + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

2 ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-L-lysyl-(glycyl)₅-D-alanyl-D-alanine → a peptidoglycan dimer (S. aureus) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

2 H₂O + a peptidoglycan dimer (meso-diaminopimelate containing) → 2 D-alanine + di-trans,octa-cis-undecaprenyl diphosphate + a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

2 a peptidoglycan dimer (E. faecium, tetrapeptide) + 3 H₂O → 4 D-alanine + a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

8 isopentenyl diphosphate + (2E,6E)-farnesyl diphosphate → 8 diphosphate + di-trans,octa-cis-undecaprenyl diphosphate

2 ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → a peptidoglycan dimer (meso-diaminopimelate containing) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

a nascent peptidoglycan with D,D cross-links (meso-diaminopimelate containing) → di-trans,octa-cis-undecaprenyl diphosphate + a mature peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + H⁺

2 ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanyl-D-alanine → a peptidoglycan dimer (E. faeciums) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

a nascent peptidoglycan with L,D cross links (meso-diaminopimelate containing) → a mature peptidoglycan with L,D cross-links (meso-diaminopimelate containing) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

M-antigen (variant) monomer undecaprenyl diphosphate + core oligosaccharide-lipid A (E. coli K-12 core type) (no GlcNAc) → M_LPS + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

a nascent peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide → a mature peptidoglycan with (L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-glycine) tetrapeptide + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

2 a peptidoglycan dimer (E. faeciums) + 3 H₂O → 4 D-alanine + a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

2 ditrans,octacis-undecaprenyldiphospho-N-acetyl-(N-acetylglucosaminyl)muramoyl-L-alanyl-γ-D-isoglutaminyl-N-(β-D-asparaginyl)-L-lysyl-D-alanine → a peptidoglycan dimer (E. faecium, tetrapeptide) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

Reversible reaction (1)

diphosphoundecaprenyl-[GlcNAc-MurNAc-pentapeptide]_n + ditrans,octacis-undecaprenyldiphospho-[(N-acetyl-β-D-glucosaminyl)-(1,4)-]-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H⁺ ↔ diphosphoundecaprenyl-[GlcNAc-MurNAc-pentapeptide]_n+1 + di-trans,octa-cis-undecaprenyl diphosphate