Compound as reactive (3)

(3E)-2-oxohex-3-enedioate + H⁺ → (2Z)-2-hydroxypenta-2,4-dienoate + CO₂

(3E)-2-oxohex-3-enedioate + H⁺ → 2-oxopent-4-enoate + CO₂

2-oxoadipate + NAD⁺ ← NADH + (3E)-2-oxohex-3-enedioate + H⁺

Compound as product (1)

H₂O + (2Z,4E)-2-aminomuconate + H⁺ → (3E)-2-oxohex-3-enedioate + ammonium

Reversible reaction (2)

4-oxalocrotonate ↔ (3E)-2-oxohex-3-enedioate

(2Z,4E)-2-hydroxyhexa-2,4-dienedioate ↔ (3E)-2-oxohex-3-enedioate