1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + oxygen → 4-(methylsulfanyl)-2-oxobutanoate + formate + H+
H+ + CO2 → formate
H2O + 2,6-dihydroxynicotinate + oxygen → maleamate + formate + H+ + CO2
H2O + formyl-CoA → coenzyme A + formate + H+
5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine → 3 H+ + 4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine + formate + 5'-deoxyadenosine + L-methionine + carbon monoxide
2 H+ + 3 NADPH + 3 oxygen + 4α,14α-dimethyl-5α-cholesta-8,24-dien-3β-ol → 3 NADP+ + 4 H2O + 4α-methyl-5α-cholesta-8,14,24-trien-3β-ol + formate
H2O + formaldehyde + NAD+ → 2 H+ + NADH + formate
H2O + 2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one → 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + H+
H2O + 2,4,6-trioxohexanoate → acetylpyruvate + formate + H+
2 a reduced ferredoxin [iron-sulfur] cluster + 30-oxolanosterol + H+ + oxygen → 2 an oxidized ferredoxin [iron-sulfur] cluster + 4,4-dimethyl-5-α-cholesta-8,14,24-trien-3-β-ol + H2O + formate
H2O + 4-deoxy-4-formamido-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate → 4-amino-4-deoxy-α-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + formate
H2O + N-Formyl-L-kynurenine → formate + L-kynurenine + H+
H2O + (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate → formate + H+ + (2Z)-2-hydroxypenta-2,4-dienoate
H2O + vinyl acetate → allyl alcohol + formate
2 NADPH + octadecanal + H+ + oxygen → 2 NADP+ + H2O + formate + heptadecane
H2O + GTP → 7,8-dihydroneopterin 2',3'-cyclic phosphate + formate + H+ + diphosphate
2 H2O + dichlorocarbene → 2 chloride + 3 H+ + formate
H2O + 5-formyl-tetrahydromethanopterin → tetrahydromethanopterin + formate + H+
H+ + oxalate → formate + CO2
H2O + N1-acetyl-N2-formyl-5-methoxykynuramine → formate + H+ + N-acetyl-5-methoxykynurenamine
H2O + octadecanal → formate + H+ + heptadecane
H2O + S-formylmycothiol → formate + mycothiol + H+
2,4'-dihydroxyacetophenone + oxygen → 2 H+ + formate + 4-hydroxybenzoate
H2O + S-formylbacillithiol → bacillithiol + formate + H+
H2O + 4-imidazolone-5-propanoate + a reduced electron donor + oxygen → an oxidized electron donor + 4-oxoglutaramate + formate + ammonium
H2O + formamide → formate + ammonium
2 H2O + 2,3-epoxy-2,3-dihydrobenzoyl-CoA → formate + cis-3,4-dehydroadipyl-CoA semialdehyde + H+
3 oxygen + 5 H+ + 6 a reduced ferredoxin [iron-sulfur] cluster + lanosterol → 4 H2O + 6 an oxidized ferredoxin [iron-sulfur] cluster + 4,4-dimethyl-5-α-cholesta-8,14,24-trien-3-β-ol + formate
H2O + formylaminopyrimidine → formate + aminomethylpyrimidine
H2O + S-formylglutathione → formate + H+ + glutathione
H2O + (R)-N-formyl-β-hydroxy-L-kynurenine → (R)-β-hydroxy-L-kynurenine + formate + H+
2 3-amino-4-hydroxybenzaldehyde + 2 oxygen + N-acetyl-L-cysteine → 3 H2O + formate + H+ + grixazone A
H2O + 2-formylaminobenzaldehyde → O-aminobenzaldehyde + formate + H+
H2O + formate + ATP → formate + phosphate + ADP
H2O + tert-butyl formate → tert-butyl alcohol + formate + H+
3 H2O + GTP → 2 H+ + 2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one + formate + diphosphate
H2O + N-formylmaleamate → maleamate + formate + H+
H2O + GTP → 7,8-dihydroneopterin 3'-triphosphate + formate + H+
2 H+ + 3 NADPH + 3 oxygen + 24,25-dihydrolanosterol → 3 NADP+ + 4 H2O + 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + formate
coenzyme A + 2-oxobutanoate → propanoyl-CoA + formate
intermediate IV → akuammicine + formate + H+
H2O + N-formyl-L-methionine → formate + L-methionine
γ-L-glutamyl-(S)-2-carboxypropyl-L-cysteine → γ-L-glutamyl-(S)-trans-1-propenyl-L-cysteine + formate
H2O + N-formyl-L-glutamate → formate + L-glutamate
2 H+ + 3 NADPH + 3 oxygen + obtusifoliol → 3 NADP+ + 4 H2O + 4α-methyl-5α-ergosta-8,14,24(28)-trien-3β-ol + formate
1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + oxygen → formate + 3-(methylsulfanyl)propanoate + H+ + carbon monoxide
H2O + formyl-L-isoglutamine → formate + L-isoglutamine
4,4-dimethyl-14α-formyl-5α-cholesta-8-en-3β-ol + NADPH + oxygen → 4,4-dimethyl-5-α-cholesta-8,14-dien-3-β-ol + H2O + formate + NADP+
2-hydroxyethylphosphonate + oxygen → formate + hydroxymethylphosphonate + H+
H2O + (2Z,4E)-2-hydroxy-6-oxohexa-2,4-dienoate → 2-oxopent-4-enoate + formate + H+
5-amino-1-(5-phospho-β-D-ribosyl)imidazole + S-adenosyl-L-methionine + a reduced electron donor → 2 H+ + an oxidized electron donor + 5-hydroxybenzimidazole + formate + ammonium + 5'-deoxyadenosine + L-methionine + phosphate
H2O + N-formyldemecolcine → formate + demecolcine
2 oxygen + Latia luciferin + a reduced unknown two electron carrier → Latia oxyluciferin + formate + CO2 + H2O + an oxidized unknown electron carrier + H+ + hν
D-ribulose 5-phosphate → 1-deoxy-L-glycero-tetrulose 4-phosphate + formate + H+
5-(methylsulfanyl)-2,3-dioxopentyl 1-phosphate + 3 H2O → 4-(methylsulfanyl)-2-oxobutanoate + formate + 6 H+ + phosphate
2 H+ + lanosterol + 3 NADPH + 3 oxygen → 4,4-dimethyl-5-α-cholesta-8,14,24-trien-3-β-ol + formate + 4 H2O + 3 NADP+