Compound as reactive (1)
H2O + S-formylglutathione → formate + H+ + glutathione
Compound as product (1)
formaldehyde + glutathione + NAD+ → H+ + NADH + S-formylglutathione
Reversible reaction (2)
NAD+ + S-(hydroxymethyl)glutathione ↔ NADH + H+ + S-formylglutathione
NAD(P)+ + S-(hydroxymethyl)glutathione ↔ NAD(P)H + H+ + S-formylglutathione