Compound as reactive (7)
L-phenylalanine + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → H2O + L-tyrosine + (6R)-6,7-dihydrobiopterin
L-phenylalanine + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → L-tyrosine + (6R)-4a-hydroxy-tetrahydrobiopterin
anthranilate + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → H2O + L-erythro-7,8-dihydrobiopterin + 3-hydroxyanthranilate
L-phenylalanine + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → (6R)-4a-hydroxy-tetrahydrobiopterin + 3-hydroxy-L-phenylalanine
1-O-alkyl-sn-glycerol + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + oxygen → H2O + L-erythro-7,8-dihydrobiopterin + 1-(1-hydroxyalkyl)-sn-glycerol
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tyrosine + oxygen → L-dopa + (6R)-4a-hydroxy-tetrahydrobiopterin
(6R)-L-erythro-5,6,7,8-tetrahydrobiopterin + L-tryptophan + oxygen → 5-hydroxy-L-tryptophan + (6R)-4a-hydroxy-tetrahydrobiopterin
Compound as product (4)
2 NADP+ + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin ← 2 NADPH + 2 H+ + (6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin
NAD+ + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin ← L-erythro-7,8-dihydrobiopterin + NADH + H+
NADP+ + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin ← NADPH + H+ + (6R)-6-lactoyl-5,6,7,8-tetrahydropterin
NAD(P)+ + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin ← NAD(P)H + H+ + (6R)-6,7-dihydrobiopterin
Reversible reaction (1)
2 NADP+ + (6R)-L-erythro-5,6,7,8-tetrahydrobiopterin ↔ 2 NADPH + 2 H+ + L-erythro-biopterin