Compound as reactive (1)

3-methylcrotonyl-CoA + hydrogencarbonate + ATP → H⁺ + 3-methylglutaconyl-CoA + phosphate + ADP

Compound as product (2)

coenzyme A + 5-methyl-3-oxo-4-hexenoyl-CoA → acetyl-CoA + 3-methylcrotonyl-CoA

FAD + H⁺ + isovaleryl-CoA → FADH₂ + 3-methylcrotonyl-CoA

Reversible reaction (1)

an oxidized electron donor + isovaleryl-CoA ↔ a reduced electron donor + 3-methylcrotonyl-CoA