Compound as reactive (15)

L-leucine + (-)-jasmonate + ATP → H⁺ + diphosphate + (-)-jasmonoyl-L-leucine + AMP

H⁺ + L-leucine + LEU-tRNAs + ATP → Charged-LEU-tRNAs + diphosphate + AMP

10 ATP + 3 L-threonine + 6 L-2,4-diaminobutanoate + L-leucine + 6-methyloctanoyl-CoA → 10 diphosphate + 10 AMP + 11 H⁺ + coenzyme A + polymyxin A

L-leucine + demethylarginomycin + ATP → H⁺ + phosphate + L-leucyl-demethylarginomycin + ADP

L-leucine + ATP + (indol-3-yl)acetate → (indol-3-yl)acetyl-L-leucine + H⁺ + diphosphate + AMP

H₂O + L-leucine + ATP → L-leucine + phosphate + ADP

2-oxoglutarate + L-leucine + oxygen → 5-hydroxy-leucine + succinate + CO₂

2-oxoglutarate + L-leucine + oxygen → 4-hydroxy-L-leucine + succinate + CO₂

H₂O + NAD⁺ + L-leucine → NADH + 4-methyl-2-oxopentanoate + H⁺ + ammonium

N-3-fumaramoyl-L-2,3-diaminopropanoate + L-leucine + ATP → dapdiamide C + H⁺ + phosphate + ADP

L-leucine + demethylblasticidin S + ATP → H⁺ + phosphate + L-leucyl-demethyl-blasticidin S + ADP

ATP + L-leucine + tRNA(Leu), mitochondrial → AMP + diphosphate + Leu-tRNA(Leu)

L-leucine + Na⁺ → L-leucine + Na⁺

L-leucine + H⁺ → L-leucine + H⁺

L-leucine + H⁺ → L-leucine + H⁺

Compound as product (8)

H₂O + L-alanyl-L-leucine → L-leucine + L-alanine

H₂O + L-leucyl-arginomycin → arginomycin + L-leucine

H₂O + L-leucyl-blasticidin S → blasticidin S + L-leucine

H₂O + L-leucine + ATP → L-leucine + phosphate + ADP

H₂O + (indol-3-yl)acetyl-L-leucine → L-leucine + (indol-3-yl)acetate

L-leucine + Na⁺ → L-leucine + Na⁺

L-leucine + H⁺ → L-leucine + H⁺

L-leucine + H⁺ → L-leucine + H⁺

Reversible reaction (5)

L-leucine ↔ (3R)-β-leucine

acetyl-CoA + L-leucine ↔ coenzyme A + N-acetyl-L-leucine + H⁺

H₂O + N(α)-benzyloxycarbonyl-L-leucine + H⁺ ↔ benzyl alcohol + L-leucine + CO₂

2-oxoglutarate + L-leucine ↔ 4-methyl-2-oxopentanoate + L-glutamate

H₂O + NADP⁺ + L-leucine ↔ ammonia + NADPH + 4-methyl-2-oxopentanoate