Compound as reactive (3)

H₂O + N^ω-hydroxy-L-arginine → hydroxyurea + L-ornithine

2 N^ω-hydroxy-L-arginine + 2 oxygen + NADPH → 2 H₂O + 2 L-citrulline + 2 nitric oxide + NADP⁺ + H⁺

N^ω-hydroxy-L-arginine → H₂O + guanidinium + H⁺ + (S)-1-pyrroline-5-carboxylate

Compound as product (2)

2 NADPH + 2 H⁺ + 2 L-arginine + 2 oxygen → 2 H₂O + 2 NADP⁺ + 2 N^ω-hydroxy-L-arginine

2-oxoglutarate + L-arginine + oxygen → N^ω-hydroxy-L-arginine + succinate + CO₂

Reversible reaction (2)

2 NAD(P)H + 2 H⁺ + 2 L-arginine + 2 oxygen ↔ 2 H₂O + 2 NAD(P)+ + 2 N^ω-hydroxy-L-arginine

2 N^ω-hydroxy-L-arginine + 2 oxygen + NAD(P)H ↔ 2 H₂O + 2 L-citrulline + 2 nitric oxide + NAD(P)+ + H⁺