Compound as reactive (1)

3 oxygen + protoporphyrinogen IX → 3 hydrogen peroxide + protoporphyrin IX

Compound as product (4)

NAD(P)+ + coproporphyrinogen III → 2 CO₂ + NAD(P)H + protoporphyrinogen IX

2 S-adenosyl-L-methionine + coproporphyrinogen III → 2 5'-deoxyadenosine + 2 L-methionine + 2 CO₂ + protoporphyrinogen IX

2 H⁺ + oxygen + coproporphyrinogen III → 2 H₂O + 2 CO₂ + protoporphyrinogen IX

2 oxygen + coproporphyrinogen III → 2 hydrogen peroxide + 2 CO₂ + protoporphyrinogen IX

Reversible reaction (2)

3 oxygen + protoporphyrinogen IX ↔ 6 H₂O + protoporphyrin IX

an oxidized electron donor + protoporphyrinogen IX ↔ a reduced electron donor + protoporphyrin IX