Compound as reactive (8)

(R)-lactate + ATP + D-alanine → D-alanyl-D-lactate + phosphate + ADP

2 D-alanine + ATP → D-alanyl-D-alanine + H⁺ + phosphate + ADP

H⁺ + ATP + D-alanine → (D-alanyl)adenylate + diphosphate

L-glutamine + D-alanine → ammonium + γ-L-glutamyl-D-alanine

H₂O + D-alanine → ammonia + pyruvate

poly(ribitol phosphate) + ATP + D-alanine → O-D-alanyl-poly(ribitol phosphate) + H⁺ + diphosphate + AMP

H₂O + oxygen + D-alanine → hydrogen peroxide + pyruvate + ammonium

ATP + D-serine + D-alanine → D-alanyl-D-serine + H⁺ + phosphate + ADP

Compound as product (18)

2 a peptidoglycan dimer (S. aureus) + 3 H₂O → 4 D-alanine + a peptidoglycan with D,D cross-link (S. aureus) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

2 a peptidoglycan dimer (meso-diaminopimelate containing) + H₂O → a peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine

H₂O + N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanine → N-acetyl-D-glucosaminyl-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysine + D-alanine

2 a peptidoglycan dimer (meso-diaminopimelate containing) → a peptidoglycan with D,D cross-links (meso-diaminopimelate containing) + D-alanine

2 a peptidoglycan dimer (mycobacteria) + 4 H₂O → 4 D-alanine + a peptidoglycan with D,D cross-links (mycobacteria) + H⁺ + mono-trans,octa-cis-decaprenyl diphosphate

2 a peptidoglycan dimer (S. aureus) → a peptidoglycan with D,D cross-link (S. aureus) + D-alanine

2 a peptidoglycan dimer (mycobacteria) + 4 H₂O → 4 D-alanine + a peptidoglycan with L,D cross-links (mycobacteria) + H⁺ + mono-trans,octa-cis-decaprenyl diphosphate

H₂O + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine → UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine + D-alanine

2 H₂O + a peptidoglycan dimer (meso-diaminopimelate containing) → 2 D-alanine + di-trans,octa-cis-undecaprenyl diphosphate + a peptidoglycan with D,D cross-links (meso-diaminopimelate containing)

2 a peptidoglycan dimer (E. faecium, tetrapeptide) + 3 H₂O → 4 D-alanine + a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

2 a peptidoglycan dimer (E. faecium, tetrapeptide) + H⁺ → a peptidoglycan tetramer with an L,D cross-link (Enterococcus faecium) + D-alanine

H₂O + L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine → L-alanyl-γ-D-glutamyl-meso-diaminopimelate + D-alanine

2 a peptidoglycan dimer (E. faeciums) + H⁺ → a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium) + D-alanine

H₂O + D-alanyl-D-alanine → 2 D-alanine

H₂O + UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + D-alanine

H₂O + UDP-N-acetylmuramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanine → UDP-N-acetyl-α-D-muramoyl-L-alanyl-γ-D-glutamyl-meso-2,6-diaminopimelate + D-alanine

2 a peptidoglycan dimer (E. faeciums) + 3 H₂O → 4 D-alanine + a peptidoglycan tetramer with a D,D cross-link (Enterococcus faecium) + di-trans,octa-cis-undecaprenyl diphosphate + H⁺

[(4-D-Ala)-(2-GlcNAc)-Rib-ol-P]n-Gro-P-Gro-P-β-D-ManNAc-(1→4)-α-D-GlcNAc-P-peptidoglycan + n H₂O → [(2-GlcNAc)-Rib-ol-P]n-Gro-P-Gro-P-β-D-ManNAc-(1→4)-α-D-GlcNAc-PP-peptidoglycan + n D-alanine + n H⁺

Reversible reaction (7)

H₂O + L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine ↔ L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine + D-alanine

2-oxoglutarate + D-alanine ↔ pyruvate + D-glutamate

N-acetyl-muramoyl-(L-alanyl-γ-D-glutamyl-L-lysyl-D-alanyl-D-alanine) + H₂O ↔ N-acetyl-muramoyl-(L-alanyl-γ-D-glutamyl-L-lysyl-D-alanine) + D-alanine

coenzyme A + (2R)-2-amino-4-oxopentanoate ↔ acetyl-CoA + D-alanine

L-alanine ↔ D-alanine

pyridoxal 5'-phosphate + D-alanine ↔ pyruvate + pyridoxamine 5'-phosphate

H₂O + Nα,Nε-diacetyl-lysyl-D-alanyl-D-alanine ↔ H⁺ + Nα,Nε-diacetyl-lysyl-D-alanine + D-alanine