an oxidized electron donor

a reduced electron donor

a deaminated amino group acceptor

an aminated amino group acceptor

Charged-LEU-tRNAs

LEU-tRNAs

a 2-oxo acid

an amino acid

an acyl-CoA

a carboxylate

an oxidized ferredoxin [iron-sulfur] cluster

a reduced ferredoxin [iron-sulfur] cluster

NAD(P)H

NAD(P)+

an L-tyrosyl-[tRNAtyr]

a tRNAtyr

(2Z,4Z)-2-hydroxy-5-carboxymuconate-6-semialdehyde

4α,14α-dimethyl-porifersta-8,25(27)-dienol

2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate

4-methylcyclohex-1,5-diene-1-carbonyl-CoA

isoshowacene

2-hydroxyhexadecanal

16-sinapoyloxypalmitate

3-methylquinolin-2-ol

(22R)-hydroxycholesterol

N-(2-methylpropyl)hydroxylamine

chloroeremomycin

3-hydroxy-3-methylbutanoate

2',3',4'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2',3'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

2'-O-methyl-rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tetracyclic spinosyn pseudoaglycone

rhamnosyl tricyclic spinosyn pseudoaglycone

spinosyn tricyclic macrolactone

11-dehydro-15-oxo spinosyn macrolactone

15-oxo spinosyn macrolactone

spinosyn macrolactone

diethylamine N-oxide

triethylamine N-oxide

UDP-2-acetamido-2-deoxy-α-D-ribo-hex-3-uluronate

nitroxyl

trans,octacis-decaprenylphospho-β-D-arabinofuranose

1,3-dihydro-2H-imidazol-2-one

2-phenylethyl β-D-glucopyranoside

formyl hopane

ribosyl hopane

adenosyl hopane

(2Z)-2-hydroxypenta-2,4-dienoate

(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate

(2Z)-2,4-dihydroxypent-2-enoate

(2E,7Z,10Z,13Z,16Z,19Z)-docosahexaenoyl-CoA

(3R,5Z,8Z,11Z,14Z,17Z)-3-hydroxydocosapentaenoyl-CoA

(5Z,8Z,11Z,14Z,17Z)-3-oxodocosapentaenoyl-CoA

(+)-3'-hydroxylarreatricin

(+)-larreatricin

2-trans,4-trans-xanthoxin

glycolate

H₂O

2-phosphoglycolate

N-(5-phosphoribosyl)-anthranilate

O-acetyl-L-serine

H₂

CO₂

thiamine phosphate

4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine

3-methyl-2-oxobutanoate

6-aminohexanoate

6-aminohexanoate linear dimer

5-methylcytosine

carbonic acid

5-oxo-L-proline

3-phosphooxypyruvate

4-phosphooxy-L-threonine

(3R)-3-hydroxy-2-oxo-4 phosphooxybutanoate

(S)-2-acetolactate

(S)-2-aceto-2-hydroxybutanoate

phosphoenolpyruvate

anthranilate

2-(formamido)-N¹-(5-phospho-β-D-ribosyl)acetamidine

N²-formyl-N¹-(5-phospho-β-D-ribosyl)glycinamide

(2S)-2-isopropylmalate

oxaloacetate

(indol-3 yl)acetyl-CoA

(indol-3-yl)pyruvate

hydrogen peroxide

S-methyl-5-thio-α-D-ribose 1-phosphate

S-methyl-5'-thioadenosine

5-deoxy-α-ribose 1-phosphate

(2R,3S)-3-isopropylmalate

2-isopropylmaleate

shikimate 3-phosphate

shikimate

prephenate

5-amino-1-(5-phospho-β-D-ribosyl)imidazole

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate

succinate semialdehyde

L-arginino-succinate

L-canavanine

canavaninosuccinate

carbon monoxide

(R)-4'-phosphopantothenoyl-L-cysteine

(R)-4'-phosphopantothenate

4'-phosphopantetheine

3-ureidopropanoate

orotidine 5'-phosphate

propane-1,3-diamine

(S)-dihydroorotate

hydrogenobyrinate a,c-diamide

(2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate

isochorismate

prenyl diphosphate

isopentenyl diphosphate

(R)-5-phosphomevalonate

(R)-mevalonate

preuroporphyrinogen

porphobilinogen

5-aminolevulinate

(S)-4-amino-5-oxopentanoate

5-enolpyruvoyl-shikimate 3-phosphate

glycerone phosphate

citrate

imidazole acetol-phosphate

D-erythro-imidazole-glycerol-phosphate

2-oxovalerate

3-ethylmalate

4-methyl-2-oxopentanoate

(2S)-2-isopropyl-3-oxosuccinate

N-acetyl-L-glutamate 5-semialdehyde

L-histidinol phosphate

thiamine diphosphate

3-dehydroshikimate

3-dehydroquinate

3-deoxy-D-arabino-heptulosonate 7-phosphate

xanthine

N-acetylglutamyl-phosphate

carbamoyl phosphate

5-amino-6-(5-phospho-D-ribosylamino)uracil

5-amino-6-(5-phospho-D-ribitylamino)uracil

(S)-3-methyl-2-oxopentanoate

oxalosuccinate

5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole

L-β-lysine

urea

(4,5-dihydro-5-oxofuran-2-yl)-acetate

(2-carboxy-2,5-dihydro-5-oxofuran-2-yl)-acetate

glutathione disulfide

γ-L-glutamyl 5-phosphate

(R)-2,3-dihydroxy-3-methylpentanoate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoyl-CoA

nicotinate adenine dinucleotide

acetyl phosphate

N¹-(5-phospho-β-D-ribosyl)glycinamide

histidinol

histidinal

5-phospho-β-D-ribosylamine

4-amino-2-methyl-5-(phosphooxymethyl)pyrimidine

4-amino-2-methyl-5-pyrimidinemethanol

hydroxypyruvate

5-amino-6-(D-ribitylamino)uracil

CDP-glycerol

N-methylhydantoin

4-imidazoleacetate

imidazole acetaldehyde

5-hydroxyindole acetate

5-hydroxyindole acetaldehyde

3-methoxy-4-hydroxyphenylglycolaldehyde

3,4-dihydroxyphenylacetaldehyde

propynoate

prop-2-ynal

D-glucurono-6,3-lactone

4-acetamidobutanoate

4-acetamidobutanal

dimethylsulfoniopropanoate

4-aminobutanoate

3-oxopropanoate

O-ureido-L-homoserine

DNA without lesion

hydroxylamine

β-nicotinate D-ribonucleotide

2-keto-L-gulonate

coenzyme F₃₉₀-A

6-phospho D-glucono-1,5-lactone

pseudouridine 5'-phosphate

oxalate

7,8-didemethyl-8-hydroxy-5-deazariboflavin

dihydromethanophenazine

methanophenazine

4-amino-4-deoxychorismate

2-maleylacetate

N-ethylammeline

deethylsimazine

arsenite

3-(O-geranylgeranyl)-sn-glycerol 1-phosphate

4-prenylphlorisobutyrophenone

quinolinate

(R)-1-amino-2-propanol O-2-phosphate

(R)-1-aminopropan-2-ol

α-ribazole 5'-phosphate

α-ribazole

(2S)-lactyl-2-diphospho-5'-guanosine

CoB-CoM heterodisulfide

coenzyme B

acetoacetate

4-fumaryl-acetoacetate

1-deoxy-L-glycero-tetrulose 4-phosphate

hydrogenobyrinate

hexulose 6-phosphate

(L-threonylcarbamoyl)adenylate

2,5-diamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

adenosine 5'-phosphoselenate

adenosine 5'-phosphosulfate

sym-homospermidine

dialurate

5,6-dimethylbenzimidazole

2-(sulfomethyl)thiazolidine-4-carboxylate

sulfoethylcysteine

citraconate

(2R,3S)-3-methylmalate

2-(α-hydroxyethyl)thiamine diphosphate

2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one

N⁵-carboxyaminoimidazole ribonucleotide

(R)-mevalonate diphosphate

ammonia

crotonate

cyclohex-1,5-diene-1-carbonyl-CoA

6-hydroxycyclohex-1-ene-1-carbonyl-CoA

6-oxocyclohex-1-ene-1-carbonyl-CoA

3-hydroxypimeloyl-CoA

3-oxopimeloyl-CoA

cyclohexane-1-carboxylate

cyclohexane-1-carbonyl-CoA

2-hydroxy-6-oxocyclohexane-1-carbonyl-CoA

autoinducer 2

S-ribosyl-L-homocysteine

L-gulono-1,4-lactone

L-xylo-hex-3-ulono-1,4-lactone

α-D-galacturonate 1-phosphate

L-dehydro-ascorbate

pyruvic oxime

cyclic-2,3-O-oxalyl-L-threonate

dehydroascorbate (bicyclic form)

(2S,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

(2R,4S)-2-methyl-2,4-dihydroxydihydrofuran-3-one

enol-phenylpyruvate

cyclic- 3,4-O-oxalyl-L-threonate

2,3-dioxo-L-gulonate

bisorganyltrisulfane

(2S,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

(2R,4S)-2-methyl-2,3,3,4-tetrahydroxytetrahydrofuran

2-carboxy-L-xylonolactone

2-carboxy-L-threo-pentonate

(2E,6E)-farnesyl diphosphate

pristanate

2-methoxy-6-(all-trans-octaprenyl)phenol

3-(all-trans-octaprenyl)benzene-1,2-diol

5,10-methenyltetrahydrofolate mono-L-glutamate

(R)-citramalate

S-(4-hydroxy-nonenal-3-yl)-L-cysteinylglycine

(2R)-2,3-dihydroxy-3-methylbutanoate

(2S)-2-phospholactate

dTDP-4-dehydro-6-deoxy-α-D-glucopyranose

3-phospho-D-glyceroyl-phosphate

2,3-diphospho-D-glycerate

2-phospho-D-glycerate

3-phospho-D-glycerate

sn-glycerol 3-phosphate

sn-glycerol 1-phosphate

2-chloroacetate

oxygen

hydrogen sulfide

uroporphyrinogen-III

Mg-protoporphyrin

protoporphyrin IX

uroporphyrinogen-I

siroheme

N₂

cob(I)alamin

adenosylcobalamin

adenosylcobinamide

cob(I)inamide

adenosyl-cob(III)yrinate a,c-diamide

cob(I)yrinate a,c-diamide

cob(II)yrinate a,c-diamide

cobalt-sirohydrochlorin

cobalt-precorrin-2

adenosyl-cobinamide phosphate

adenosylcobyrate

adenosylcobalamin 5'-phosphate

adenosylcobinamide-GDP

cobalt-precorrin-6A

cobalt-precorrin-5B

cobyrinate

cob(II)yrinate c-monoamide

cobalt-precorrin-5A

cobalt-precorrin-4

cobalt-precorrin-6B

cobalt-precorrin-8

cobalt-precorrin-7

cobalt-precorrin-3

cobalt-factor III

ethylphosphate

phenylacetate

DNA with lesion

L-homocysteine

N-acetyl-L-glutaminyl-L-glutamine amide

N-acetyl-L-glutaminyl-L-glutamine

2-iminosuccinate

2-iminobutanoate

2-iminopropanoate

L-arginine

L-histidine

L-lysine

L-glutamate

L-serine

L-glutamine

L-alanine

glycine

L-leucine

L-proline

N-carbamoylsarcosine

β-alanine

L-isoleucine

L-tryptophan

L-phenylalanine

L-valine

L-methionine

L-cysteine

L-threonine

L-ornithine

L-cystathionine

L-asparagine

L-aspartate

L-tyrosine

L-aspartyl-4-phosphate

N-carbamoyl-L-aspartate

N-acetyl-L-ornithine

L-citrulline

S-adenosyl-L-homocysteine

S-adenosyl-L-methionine

O-succinyl-L-homoserine

L-aspartate 4-semialdehyde

L-homoserine

L-glutamate-5-semialdehyde

O-phospho-L-homoserine

L-cystine

meso-diaminopimelate

S-(4-hydroxy-nonenal-3-yl)-L-cysteine

L-selenomethionine

seleno-L-homocysteine

S-sulfanyl-L-cysteine

3-phospho-L-serine

N-carbamoylglycine

N-acetyl-L-glutamate

N-acetyl-L-methionine

AMP

ATP

ADP

5'-deoxyadenosine

hypoxanthine

dADP

GDP

dGDP

dATP

dGTP

GTP

ITP

IDP

dITP

dIDP

1-(5-phospho-β-D-ribosyl)-AMP

1-(5-phospho-β-D-ribosyl)-ATP

GMP

XMP

adenylo-succinate

IMP

cyclic-AMP

2'-deoxyguanosine

2'-deoxyadenosine

dGMP

dAMP

5-fluorocytosine

NAD⁺

NADP⁺

NADH

NADPH

5,6-dihydrouracil

5,6-dihydrothymine

ADP-D-ribose

ADP ribose 1''-phosphate

ADP ribose 1'',2''-cyclic phosphate

GDP-α-D-mannose

GDP-4-dehydro-α-D-rhamnose

GDP-4-dehydro-6-deoxy-β-L-galactose

GDP-β-L-fucose

dTDP-α-D-glucose

dTDP-4-dehydro-β-L-rhamnose

dTDP-β-L-rhamnose

UDP-N-acetyl-α-D-mannosamine

UDP-α-D-galactose

UDP-α-D-glucose

UDP-α-D-glucuronate

UDP-α-D-galacturonate

UDP-N-acetyl-α-D-glucosamine

UDP-N-acetyl-α-D-galactosamine

UDP-N-acetyl-α-D-mannosaminuronate

adenine

uracil

cytosine

thymine

dUMP

dCMP

dTMP

dCDP

dUDP

dTDP

dCTP

dTTP

dUTP

CDP

UDP

β-nicotinamide D-ribonucleotide

CTP

UTP

CMP

UMP

thymidine

2'-deoxycytidine

2'-deoxyuridine

adenosine

xanthosine

uridine

cytidine

5-fluorouracil

L-gulonate

aldehydo-L-galactonate

aldehydo-D-galacturonate

sucrose 6^F-phosphate

D-ribulose-1,5-bisphosphate

D-galactosylononitol

galactinol

1-(o-carboxyphenylamino)-1'-deoxyribulose 5'-phosphate

5-phospho-α-D-ribose 1-diphosphate

D-erythrose 4-phosphate

L-fuculose 1-phosphate

α-D-glucopyranose 1-phosphate

α-D-mannose 1-phosphate

β-D-fructofuranose 1-phosphate

β-D-glucopyranose 1-phosphate

β-D-fructofuranose 6-phosphate

β-D-fructose 1,6-bisphosphate

D-fructose 6-phosphate

β-D-glucose 6-phosphate

α-D-glucose 6-phosphate

α-D-mannopyranose 6-phosphate

β-D-mannopyranose 6-phosphate

α-D-ribose-1-phosphate

2-deoxy-α-D-ribose 1-phosphate

L-xylulose 5-phosphate

aldehydo-D-ribose 5-phosphate

D-ribulose 5-phosphate

L-ribulose 5-phosphate

D-glyceraldehyde 3-phosphate

β-D-fructofuranose

D-glyceraldehyde

glycolaldehyde

aldehydo-D-ribose

β-D-ribofuranose

α-D-ribofuranose

β-D-glucopyranose

α-D-glucopyranose

L-sorbosone 2,6-lactone

L-sorbosone 1,4-lactone

maltotriose

sucrose

maltotetraose

maltopentaose

maltohexaose

maltoheptaose

phlorisovalerophenone

salicylaldehyde

deoxycohumulone

4-prenylphlorisovalerophenone

deoxyhumulone

phytyl diphosphate

(3S)-linalool

(3R)-linalool

geranyl diphosphate

unsaturated CDP-archaeol

saturated CDP-archaeol

2,3-bis-O-(geranylgeranyl)-sn-glycerol 1-phosphate

2,3-bis-O-phytanyl-sn-glycerol 1-phosphate

di-trans,octa-cis-undecaprenyl diphosphate

geranylgeranyl diphosphate

ethanol

methanol

myo-inositol

scyllo-inosose

1D-myo-inositol 3-monophosphate

1D-myo-inositol 4-monophosphate

1D-myo-inositol 5-monophosphate

1D-myo-inositol 6-monophosphate

1D-myo-inositol 1-monophosphate

1D-myo-inositol 2-monophosphate

D-ononitol

3,4-dihydroxymandelate

3,4-dihydroxyphenylglycolaldehyde

3,4-dihydroxyphenylacetate

(2E,6E)-farnesal

benzaldehyde

phytenal

(S)-lactaldehyde

acetaldehyde

formaldehyde

1-octanal

methylglyoxal

(R)-acetoin

diacetyl

octanoate

decanoate

(2E,6E)-farnesoate

acetate

pyruvate

formate

propanoate

(R)-lactate

(S)-lactate

butanoate

cis-aconitate

D-threo-isocitrate

3-(carbamoylamino)-2-methylpropanoate

chorismate

D-glucarate

succinate

fumarate

(S)-malate

2-oxoglutarate

2-oxobutanoate

3-phenyl-2-oxopropanoate

3-(4-hydroxyphenyl)pyruvate

salicylate

4-aminobenzoate

benzoate

orotate

aldehydo-D-glucuronate

(S)-1-pyrroline-5-carboxylate

palmitate

α-linolenate

(5Z,8Z,11Z,14Z,17Z)-icosapentaenoate

oleate

linoleate

(15Z)-tetracosenoate

phytenate

4-hydroxybenzoate

vanillyl mandelate

2-amino-5-formylamino-6-(5-phospho-D-ribosylamino)pyrimidin-4(3H)-one

tyramine

phenol

3-demethylubiquinol-8

demethylmenaquinol-8

menaquinol-8

ubiquinol-8

indole

(indol-3-yl)acetaldehyde

(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate

(indole-3-yl)acetonitrile

tetrahydromethanopterin

(6R)-6-pyruvoyl-5,6,7,8-tetrahydropterin

5-methyl-tetrahydrosarcinapterin

tetrahydrosarcinapterin

(7,8-dihydropterin-6-yl)methyl diphosphate

7,8-dihydroneopterin 2',3'-cyclic phosphate

7,8-dihydroneopterin 3'-triphosphate

6-(hydroxymethyl)-7,8-dihydropterin

7,8-dihydroneopterin

7,8-dihydroneopterin 3'-phosphate

7,8-dihydroneopterin 2'-phosphate

7,8-dihydropteroate

7,8-dihydrofolate monoglutamate

tetrahydropteroyl tri-L-glutamate

5,6,7,8-tetrahydrofolate

(6S)-5-formyl-tetrahydrofolate mono-L-glutamate

5-methyltetrahydropteroyl tri-L-glutamate

5-methyltetrahydropteroyl mono-L-glutamate

10-formyl-tetrahydrofolate mono-L-glutamate

5,10-methylenetetrahydropteroyl mono-L-glutamate

5-formyl-tetrahydromethanopterin

5,10-methenyltetrahydromethanopterin

N⁵-methyltetrahydromethanopterin

5,10-methylene-tetrahydromethanopterin

riboflavin

FMN

FAD

reduced riboflavin

FMNH₂

6,7-dimethyl-8-(1-D-ribityl)lumazine

hydantoin

sirohydrochlorin

precorrin-6B

precorrin-8x

precorrin-7

precorrin-3A

precorrin-2

precorrin-5

precorrin-4

precorrin-3B

precorrin-1

precorrin-6A

thiamine

nicotinate

L-ascorbate

pyridoxal 5'-phosphate

coenzyme A

methyl-CoM

coenzyme M

oxidized coenzyme F₄₂₀-2

oxidized coenzyme F₄₂₀-0

(R)-NADHX

(S)-NADHX

trans-dienelactone

cis-dienelactone

L-galactono-1,4-lactone

acetyl-CoA

isobutanoyl-CoA

2-methylacetoacetyl-CoA

α-linolenoyl-CoA

linoleoyl-CoA

3'-dephospho-CoA

(S)-3-hydroxy-3-methylglutaryl-CoA

phenylacetyl-CoA

succinyl-CoA

(E)-glutaconyl-CoA

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA

(E)-2-methylcrotonoyl-CoA

2-methylbutanoyl-CoA

glutaryl-CoA

oleoyl-CoA

acetoacetyl-CoA

3-oxopentanoyl-CoA

palmitoyl-CoA

pristanoyl-CoA

octanoyl-CoA

decanoyl-CoA

propanoyl-CoA

butanoyl-CoA

(Z)-15-tetracosenoyl-CoA

(S)-3-hydroxybutanoyl-CoA

(3R)-3-hydroxybutanoyl-CoA

phytenoyl-CoA

crotonyl-CoA

(indol-3-yl)acetate

methane

1-(5-phospho-β-D-ribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide

5-amino-4-imidazolecarboxyamide

5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide

phosphoribulosylformimino-AICAR-phosphate

5-formamido-1-(5-phospho-D-ribosyl)-imidazole-4-carboxamide

agmatine

putrescine

spermidine

dehydrospermidine

spermine

N-acetylputrescine

N¹-acetylspermine

N¹-acetylspermidine

(2Z)-2-aminobut-2-enoate

2-aminoprop-2-enoate

trimethyl sulfonium

sulfate

sulfite

selenate

hydrogencarbonate

superoxide

phosphate

diphosphate

triphosphate

chloride

Fe²⁺

Mg²⁺

Co²⁺

K⁺

H⁺

ammonium

S-(hydroxymethyl)glutathione

3-dimethylsulfoniopropionaldehyde

dimethyl sulfide

glutathione

(R)-S-lactoylglutathione

3-sulfopyruvate

L-cysteate

sulfoacetaldehyde

2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate

2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate

4-methyl-5-(2-phosphooxyethyl)thiazole

5-(2-hydroxyethyl)-4-methylthiazole

S-sulfanylglutathione

monodehydroascorbate radical