Titer in Flask for 5-aminolevulinate

Strain Production
mg/L
2000
4000
6000
8000
10000
E. coli ALA1
E. coli ALA2
E. coli ALA4
E. coli ALA5
E. coli ALA6
E. coli ALA3
E. coli ALA7
E. coli ALA8
E. coli ALA9
E. coli ALA21
E. coli ALA17
E. coli ALA10
E. coli ALA11
E. coli ALA12
E. coli ALA18
E. coli ALA25
E. coli ALA16
E. coli ALA15
E. coli ALA19
E. coli ALA20
E. coli ALA22
E. coli ALA13
E. coli ALA23
E. coli ALA24
E. coli ALA14

Titer in Fed-Batch for 5-aminolevulinate

Strain Production
mg/L
8000.0
16000.0
24000.0
32000.0
40000.0
E. coli ALA14
E. coli ALA26

Substrate yield in Flask for 5-aminolevulinate

Strain Production
g/g of sustrate
0.1
0.2
0.3
0.4
0.5
E. coli ALA1
E. coli ALA2
E. coli ALA5
E. coli ALA4
E. coli ALA6
E. coli ALA3
E. coli ALA7
E. coli ALA21
E. coli ALA8
E. coli ALA17
E. coli ALA9
E. coli ALA10
E. coli ALA12
E. coli ALA11
E. coli ALA16
E. coli ALA15
E. coli ALA13
E. coli ALA22
E. coli ALA19
E. coli ALA14
E. coli ALA20
E. coli ALA18

Substrate yield in Fed-Batch for 5-aminolevulinate

Strain Production
g/g of sustrate
0.08
0.16
0.24
0.32
0.4
E. coli ALA26

Volumetric productivity in Fed-Batch for 5-aminolevulinate

Strain Production
mg/L/h
300.0
600.0
900.0
1200.0
1500.0
E. coli ALA26