Escherichia coli TRTH

Ancestors
Derived strains

Genotype with respect to parental

trpEDCBA+TetR, ΔtnaA


Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | trpEDCBA+TetR, ΔtnaA

Bars (|) indicate differences between strains.


Modifications
Gene Organism Modification
Overexpression
Overexpression
Overexpression
Overexpression
Overexpression
Silencing

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-tryptophan Titer 46.8 g/L 51.2 g/L 38 h Fed-Batch [196]
L-tryptophan Substrate yield 17.2 % 51.2 g/L 38 h Fed-Batch [196]
acetate Titer 1.19 g/L 51.2 g/L 38 h Fed-Batch [196]
L-glutamate Titer 3.28 g/L 51.2 g/L 38 h Fed-Batch [196]
L-tryptophan Titer 32.2 g/L * 36 h Fed-Batch [153]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References