Escherichia coli HS
Ancestors
Derived strains
- Escherichia coli HS1
- Escherichia coli HS2
- Escherichia coli HS5
- Escherichia coli HS6
- Escherichia coli HS7
- Escherichia coli HS9
Genotype with respect to parental
ΔJIB* ΔthrB ΔmetA ΔlysA ΔiclR ΔptsG ΔgalR ΔlacI::Ptrc-rhtA Ptrc-rhtA Ptrc-eamA Ptrc-metL Ptrc-thrA Ptrc-glk Ptrc-gltB
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔJIB* ΔthrB ΔmetA ΔlysA ΔiclR ΔptsG ΔgalR ΔlacI::Ptrc-rhtA Ptrc-rhtA Ptrc-eamA Ptrc-metL Ptrc-thrA Ptrc-glk Ptrc-gltBBars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
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Silencing
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Silencing
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Silencing
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Silencing
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Silencing
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Silencing
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Silencing
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-homoserine | Titer | 7.31 g/L * | 11.61 OD600* | Flask | [255] | ||
| L-homoserine | Titer | 13.39 g/L * | Flask | [255] | |||
| L-homoserine | Titer | 13.39 g/L * | 13.29 OD600* | Flask | [255] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.