Escherichia coli Dpta/mtr-Y

Ancestors

Genotype with respect to parental

Δpta Δmtr


Genotype with respect to wild type
F+ (λ) | ΔtrpR Δtna | Plasmid pSV-709 added | Plasmid pMEL03 added | Δpta Δmtr | Plasmid pMEL03 lost | Plasmid pMEL03-Y added

Bars (|) indicate differences between strains.


Plasmids

Modifications
Gene Organism Modification
mtr
Silencing
pta
Silencing

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-tryptophan Substrate yield 21.87 % 50.53 g/L 36 h Fed-Batch [133]
L-tryptophan Titer 46.68 g/L 50.53 g/L 36 h Fed-Batch [133]
acetate Titer 0.95 g/L 50.53 g/L 36 h Fed-Batch [133]
pyruvate Titer 2.5 mM 36 h Fed-Batch [133]
(R)-lactate Titer 29.9 mM 36 h Fed-Batch [133]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References