Escherichia coli HGB6
Ancestors
Derived strains
Genotype with respect to parental
ΔaroP and tyrP
Genotype with respect to wild type
F+ (λ) | l-Tyrosine auxotrophic | ΔtyrR, pheA and trpE | Plasmid pAP11 added | ΔaroP and tyrP | Plasmid pAP11 lost | Plasmid pAP31 addedBars (|) indicate differences between strains.
Plasmids
-
pAP31 (pAP with aroGfbr, tyrAfbr, tktA, ppsA and yddG, p15A ori with PRPL)
Strain derived from a randomly mutated strain.
Modifications
| Gene | Organism | Modification |
|---|---|---|
|
Silencing
|
||
|
Silencing
|
Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-tyrosine | Titer | 4.94 g/L * | 12.0 OD600* | Flask | [268] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.