Escherichia coli HM4 (pBRmetL)
Ancestors
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔlacI | ΔlysA | ΔmetA | ΔthrBC | Plasmid pBRmetL addedBars (|) indicate differences between strains.
Plasmids
-
pBRmetL (metL)
Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-homoserine | Titer | 1.04 g/L | 44 h | Flask | [272] | ||
| L-homoserine | Titer | 6.78 g/L | 44 h | Fed-Batch | [272] | ||
| L-homoserine | Substrate yield | 0.13 g/g of sustrate | 5.29 g/L | 44 h | Fed-Batch | [272] | |
| L-homoserine | Titer | 6.78 g/L | 5.29 g/L | 44 h | Fed-Batch | [272] | |
| acetate | Titer | 1.3 g/L | 5.29 g/L | 44 h | Fed-Batch | [272] | |
| acetate | Substrate yield | 0.025 g/g of sustrate | 5.29 g/L | 44 h | Fed-Batch | [272] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.