Escherichia coli Arg0

Ancestors

Derived strains

Genotype with respect to parental

argAK204T, argRY33X, pyrGD450H, and speBE189A


Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | argAK204T, argRY33X, pyrGD450H, and speBE189A

Bars (|) indicate differences between strains.


Strain generated through random mutagenesis.


Modifications
Gene Organism Modification
Feedback insensitive
Feedback insensitive
Silencing
Unstated
Attenuation

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-arginine Titer 34.64 g/L 48 h * Fed-Batch [301]
L-arginine Substrate yield 0.21 g/g of sustrate 48 h * Fed-Batch [301]
L-arginine Volumetric productivity 0.72 g/L/h 48 h * Fed-Batch [301]
L-citrulline Titer 2.32 g/L 48 h Fed-Batch [301]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References