Escherichia coli Arg7-8

Ancestors

All strains

Escherichia coli K12

Escherichia coli W1485

Escherichia coli MG1655

Escherichia coli Arg0

Escherichia coli Arg1

Escherichia coli Arg2

Escherichia coli Arg3

Escherichia coli Arg4

Escherichia coli Arg5

Escherichia coli Arg6

Escherichia coli Arg7

Escherichia coli Arg7-8

Genotype with respect to parental

P_BJ23104-B0034-aspC and P_BJ23109-B0034-gltA

Genotype with respect to wild type

F⁺ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | argA^K204T, argR^Y33X, pyrG^D450H, and speB^E189A | △speC △speF | argE^Ec::P_BJ23119-B0034-argJ^Tn | yghX::P_BJ23119-B0034-argCBH^Ec, yncI::P_BJ23119-B0034-argA*, rpnD::P_BJ23119-B0034-argD, ycjV::P_BJ23119-B0034-argI and yrfG::P_BJ23119-B0034-argG | artJ::P_BJ23119-B0034-lysE^Cg and argT::P_BJ23119-B0034-cgmA^Cg | yacC::P_BJ23119-B0034-gdhA^St and ydjK::P_BJ23119-B0034-gdhA^St | P_icd:P_BJ23100-B0034 | P_ppc:P_BJ23114-B0034 | P_BJ23104-B0034-aspC and P_BJ23109-B0034-gltA

Bars (|) indicate differences between strains.

Strain derived from a randomly mutated strain.

Modifications

Gene	Organism	Modification
aspC	Escherichia coli	Overexpression
gltA	Escherichia coli	Attenuation

References

Sheng, Qi; He, Shengyang; Liang, Guangjie; Meng, Gang; Zhao, Chunguang; Wei, Aiying; Gou, Lining; Liu, Jia; Li, Xiaomin; Wu, Jing & Liu, Liming. Improved arginine production in Escherichia coli by harnessing the intracellular citrulline. Metabolic Engineering. 2025.