Escherichia coli PHE01

Ancestors

Derived strains

• Escherichia coli PHE07

Genotype with respect to wild type

F⁺ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | L-tyrosine auxotrophic | Plasmid p15A::pL-aroF-tyrA^1-121-pR-pheA^T326P added

Bars (|) indicate differences between strains.

Plasmids

• p15A::pL-aroF-tyrA^1-121-pR-pheA^T326P (p15A ori, pL-aroF-tyrA^1-121-pR-pheA^T326P)

Strain derived from a randomly mutated strain.

References

• Chen, Minliang; Han, Chao; Zhou, Peng; Shi, Run; Xing, Zhiwei; Chen, Qianqian; Xie, Gou-an; Xie, Rufei; Tan, Wei & Liang, Hengyu. Rational metabolic engineering of Escherichia coli for the industrial-scale production of l-phenylalanine. Bioresource Technology. 2025, 426, 132325.