Escherichia coli PHE16

Ancestors

All strains

Escherichia coli K12

Escherichia coli W1485

Escherichia coli W2637

Escherichia coli W3110

Escherichia coli W3110MT

Escherichia coli PHE01

Escherichia coli PHE07

Escherichia coli PHE10

Escherichia coli PHE11

Escherichia coli PHE12

Escherichia coli PHE13

Escherichia coli PHE14

Escherichia coli PHE16

Genotype with respect to parental

tyrA^R197A

Genotype with respect to wild type

F⁺ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | L-tyrosine auxotrophic | Plasmid p15A::pL-aroF-tyrA^1-121-pR-pheA^T326P added | ΔfurR::furR^E173K | Plasmid p15A::pL-aroF-tyrA^1-121-pR-pheA^T326P lost | ΔdadX-cvrA:: P_J23109-aroF^fbr-P_J23107-pheA^fbr::P_J23107-aroE-P_J23110-aroD | ΔzwfΔtktAΔtktB::P_tac-xfspK | ΔylbE::pyc^P458S::PrrnC-pykFΔdhaL::pckA | ΔaspAΔmhpAΔadhE | rpoS^L33V | tyrA^R197A

Bars (|) indicate differences between strains.

Strain derived from a randomly mutated strain.

Modifications

Gene	Organism	Modification
tyrA	Escherichia coli	Feedback insensitive

References

Chen, Minliang; Han, Chao; Zhou, Peng; Shi, Run; Xing, Zhiwei; Chen, Qianqian; Xie, Gou-an; Xie, Rufei; Tan, Wei & Liang, Hengyu. Rational metabolic engineering of Escherichia coli for the industrial-scale production of l-phenylalanine. Bioresource Technology. 2025, 426, 132325.