Escherichia coli T8
Ancestors
Derived strains
- Escherichia coli T8U
- Escherichia coli T8B
- Escherichia coli T8D
- Escherichia coli T8E
- Escherichia coli T8K
- Escherichia coli T8A
- Escherichia coli T8C
- Escherichia coli T9
- Escherichia coli T8KE
Genotype with respect to parental
ΔlacI, tyrR::Ptrc-aroGS180F, trpR::Ptrc-serAH344A,N364A, trpE::Ptrc-trpES40F, ΔpykF, tktA::Ptrc-tktA, ΔptsH, yjiV::PJ23105-UTRWP1-galP, ylbE::PJ23114-UTRMK3-glk, PrpsT p1-ppc, Prrnc p1-gltA
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | ΔlacI, tyrR::Ptrc-aroGS180F, trpR::Ptrc-serAH344A,N364A, trpE::Ptrc-trpES40F, ΔpykF, tktA::Ptrc-tktA, ΔptsH, yjiV::PJ23105-UTRWP1-galP, ylbE::PJ23114-UTRMK3-glk, PrpsT p1-ppc, Prrnc p1-gltABars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
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Silencing
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Silencing
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Feedback insensitive
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Silencing
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Feedback insensitive
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Feedback insensitive
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Silencing
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Overexpression
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Silencing
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-tryptophan | Titer | 9.7 g/L | Flask | [183] | |||
| L-tryptophan | Substrate yield | 0.129 g/g of sustrate | Flask | [183] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.