Escherichia coli TC44
Ancestors
Genotype with respect to parental
Δtet
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | W3110, (Succ+), ΔfocA-pflB::FRT ΔfrdBC ΔldhA Δatp(FH)::FRT ΔadhE::FRT ΔsucA::FRT | ΔpoxB::FRT-tet-FRT | Δtet | ΔackA::FRT-tet-FRT | ΔtetBars (|) indicate differences between strains.
Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| pyruvate | Titer | 252.5 mM | 2.36 g/L | 20 h | Batch | [185] | |
| acetate | Titer | 11.6 mM | 2.36 g/L | 20 h | Batch | [185] | |
| 2-oxoglutarate | Titer | 3.6 mM | 2.36 g/L | 20 h | Batch | [185] | |
| succinate | Titer | 16.8 mM | 2.36 g/L | 20 h | Batch | [185] | |
| fumarate | Titer | 1.1 mM | 2.36 g/L | 20 h | Batch | [185] | |
| pyruvate | Titer | 749.0 mM | 2.51 g/L | Fed-Batch | [185] | ||
| acetate | Titer | 62.4 mM | 2.51 g/L | Fed-Batch | [185] | ||
| 2-oxoglutarate | Titer | 45.3 mM | 2.51 g/L | Fed-Batch | [185] | ||
| succinate | Titer | 14.7 mM | 2.51 g/L | Fed-Batch | [185] | ||
| fumarate | Titer | 3.3 mM | 2.51 g/L | Fed-Batch | [185] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.