Escherichia coli ALE-5

Ancestors

Derived strains

Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | ΔsdaA | ΔsdaB ΔtdcG | ΔglyA

Bars (|) indicate differences between strains.


Strain generated through random mutagenesis.


Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
L-serine Titer 37.3 g/L 50 h Fed-Batch [192]
L-serine Substrate yield 0.24 g/g of sustrate 50 h Fed-Batch [192]
L-serine Volumetric productivity 0.83 g/L/h 50 h Fed-Batch [192]
(S)-2-hydroxyglutarate Titer 12.1 g/L 50 h Fed-Batch [192]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References