Escherichia coli UR1
Ancestors
Derived strains
Genotype with respect to parental
△lacI, yghX::Ptrc-pyrB-pyrC-pyrAA-pyrABfbr(E949*)-pyrK-pyrD-pyrF-pyrE
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | △lacI, yghX::Ptrc-pyrB-pyrC-pyrAA-pyrABfbr(E949*)-pyrK-pyrD-pyrF-pyrEBars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
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Silencing
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Overexpression
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Overexpression
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Overexpression
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Feedback insensitive
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| uridine | Titer | 5.5 g/L | 24 h | Flask | [202] | ||
| uracil | Titer | 4.5 g/L | 32 h | Flask | [202] | ||
| uridine | Titer | 3.3 g/L | 32 h | Flask | [202] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.