Escherichia coli QH4
Ancestors
Derived strains
- Escherichia coli JW1
- Escherichia coli JW4
- Escherichia coli AA1
- Escherichia coli TP1
- Escherichia coli MA1
Genotype with respect to parental
ΔpheLA ΔtyrA
Genotype with respect to wild type
F+ (λ) | aroH367, tyrR366, tna-2, lacY5, aroF394fbr, malT384, pheA101fbr, pheO352, aroG397fbr | ΔpheLA ΔtyrABars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
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Silencing
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Silencing
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Silencing
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| anthranilate | Titer | 0.84 g/L | 48 h | Flask | [205] | ||
| anthranilate | Substrate yield | 0.054 g/g of sustrate | 48 h | Flask | [205] | ||
| L-tryptophan | Titer | 0.73 g/L | 48 h | Flask | [205] | ||
| L-tryptophan | Substrate yield | 0.037 g/g of sustrate | 48 h | Flask | [205] | ||
| cis,cis-muconate | Titer | 0.89 g/L | 48 h | Flask | [205] | ||
| cis,cis-muconate | Substrate yield | 0.071 g/g of sustrate | 48 h | Flask | [205] | ||
| anthranilate | Titer | 0.56 g/L | 48 h | Flask | [205] | ||
| anthranilate | Substrate yield | 0.046 g/g of sustrate | 48 h | Flask | [205] | ||
| L-tryptophan | Titer | 0.82 g/L | 48 h | Flask | [205] | ||
| L-tryptophan | Substrate yield | 0.05 g/g of sustrate | 48 h | Flask | [205] | ||
| cis,cis-muconate | Titer | 0.68 g/L | 48 h | Flask | [205] | ||
| cis,cis-muconate | Substrate yield | 0.059 g/g of sustrate | 48 h | Flask | [205] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.