Escherichia coli JP201

Ancestors

Derived strains

Genotype with respect to parental

pta::TnphoA′-3


Genotype with respect to wild type
supE44 hsdS20(rB−mB−) ara-14 proA2 lacY1 galK2 rpsL20 xyl-5 mtl-1 | pta::TnphoA′-3

Bars (|) indicate differences between strains.


Modifications
Gene Organism Modification
pta
Silencing

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
acetate Substrate yield 0.06 mmol/mmol of sustrate Flask [211]
ethanol Substrate yield 0.07 mmol/mmol of sustrate Flask [211]
(R)-lactate Substrate yield 1.52 mmol/mmol of sustrate Flask [211]
succinate Substrate yield 0.19 mmol/mmol of sustrate Flask [211]
pyruvate Substrate yield 0.02 mmol/mmol of sustrate Flask [211]
formate Substrate yield 0.08 mmol/mmol of sustrate Flask [211]
(R)-lactate Titer 47.0 g/L 0.9 g/L 150 h Fed-Batch [211]
(R)-lactate Titer 60.0 g/L 10.0 g/L 56 h Fed-Batch [211]
succinate Titer 9.0 g/L 10.0 g/L 56 h Fed-Batch [211]
(R)-lactate Volumetric productivity 1.09 g/L/h 10.0 g/L 56 h Fed-Batch [211]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References