Escherichia coli 7107-607
Ancestors
Derived strains
Genotype with respect to parental
ΔfucIK::T7lac–ScGNA1
Genotype with respect to wild type
F+ (λ) | λ- | inv(rrnD-rrnE) | F-, λ-, rph-1, IN (rrnD, rrnE) | F- λ- rph-1 IN(rrnD-rrnE)1 Thy | Δnag::tetR manXYZ8 DE3 | ΔgalK::T7lac–glmS*54 | ΔmanXYZ::T7lac-ScGNA1 | ΔfucIK::T7lac–ScGNA1Bars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
|
Overexpression
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Silencing
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Silencing
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| N-acetyl-β-D-glucosamine | Titer | 110.0 g/L | 72 h | Fed-Batch | [220] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.
References
- Ming-De Deng, David K. Severson, Alan D. Grund, Sarah L. Wassink, Richard P. Burlingame, Alan Berry, Jeffrey A. Running, Candice A. Kunesh, Linsheng Song, Thomas A. Jerrell & Reinhardt A. Rosson (2005). Metabolic engineering of Escherichia coli for industrial production of glucosamine and N-acetylglucosamine. Metabolic Engineering.