Escherichia coli SX1
Ancestors
Derived strains
Genotype with respect to parental
ΔtnaAB tyrR::Ptrc‐aroGfbr-serAfbr trpE::Ptrc‐trpEfbr yjiV::Ptrc‐trpBA
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | ΔtnaAB tyrR::Ptrc‐aroGfbr-serAfbr trpE::Ptrc‐trpEfbr yjiV::Ptrc‐trpBABars (|) indicate differences between strains.
Modifications
| Gene | Organism | Modification |
|---|---|---|
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Silencing
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Silencing
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Silencing
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Feedback insensitive
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Feedback insensitive
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Feedback insensitive
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Overexpression
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Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| L-tryptophan | Titer | 9.9 g/L | 9.5 g/L | Flask | [148] | ||
| L-tryptophan | Titer | 39.1 g/L | Fed-Batch | [148] | |||
| L-tryptophan | Substrate yield | 0.17 g/g of sustrate | Fed-Batch | [148] | |||
| L-tryptophan | Substrate yield | 0.13 g/g of sustrate | 9.5 g/L | Flask | [148] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.