Escherichia coli PA107

Ancestors

Derived strains

Genotype with respect to parental

ΔpoxB


Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | Grows vigorously in the presence of β-alanine | ilvG :: PM1-93-alsScgl, panBC :: PM1-93-panBC | Δglk | ΔavtA | Replacing the start codon of ilvE from ATG to GTG | ΔldhA | ΔpoxB

Bars (|) indicate differences between strains.


Strain derived from a randomly mutated strain.


Modifications
Gene Organism Modification
Silencing

Production
Metabolites Production type Production Biomass Carbon source Time Scale Ref.
(R)-pantothenate Titer 0.44 g/L 30.14 OD600* 48 h Flask [233]
(R)-pantothenate Titer 0.81 g/L 16.0 OD600* 48 h Flask [233]
(R)-pantothenate Biomass-specific titer 0.035 g/L/OD600 * 30.14 OD600* 48 h * Flask [233]
(R)-pantothenate Titer 0.5 g/L * 19.44 OD600* 60 h Flask [233]
(R)-pantothenate Biomass-specific titer 0.026 g/L/OD600 * 19.44 OD600* 60 h Flask [233]
(R)-pantothenate Biomass-specific titer 0.049 g/L/OD600 * 16.0 OD600* 60 h * Flask [233]
acetate Titer 2.05 g/L * 60 h * Flask [233]

* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.

References