Escherichia coli PA111 pCg
Ancestors
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | Grows vigorously in the presence of β-alanine | ilvG :: PM1-93-alsScgl, panBC :: PM1-93-panBC | Δglk | ΔavtA | Replacing the start codon of ilvE from ATG to GTG | ΔldhA | ΔpoxB | gltA :: PfliC-gltA | Plasmid pACYC-panBCcgl addedBars (|) indicate differences between strains.
Plasmids
-
pACYC-panBCcgl (panBCcgl)
Strain derived from a randomly mutated strain.
Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| (R)-pantothenate | Titer | 0.828 g/L * | 15.87 OD600* | Flask | [233] | ||
| (R)-pantothenate | Titer | 2.766 g/L * | 15.87 OD600* | Flask | [233] | ||
| (R)-pantothenate | Biomass-specific titer | 0.048 g/L/OD600 * | 15.87 OD600* | Flask | [233] | ||
| (R)-pantothenate | Biomass-specific titer | 0.169 g/L/OD600 * | 15.87 OD600* | Flask | [233] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.