Escherichia coli PA111 pBs
Ancestors
Genotype with respect to wild type
F+ (λ) | λ- | F- λ- ilvG- rfb-50 rph-1 | Grows vigorously in the presence of β-alanine | ilvG :: PM1-93-alsScgl, panBC :: PM1-93-panBC | Δglk | ΔavtA | Replacing the start codon of ilvE from ATG to GTG | ΔldhA | ΔpoxB | gltA :: PfliC-gltA | Plasmid pACYC-panBCbsu addedBars (|) indicate differences between strains.
Plasmids
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pACYC-panBCbsu (pACYC-panBCbsu)
Strain derived from a randomly mutated strain.
Production
| Metabolites | Production type | Production | Biomass | Carbon source | Time | Scale | Ref. |
|---|---|---|---|---|---|---|---|
| (R)-pantothenate | Titer | 0.74 g/L * | 18.57 OD600 | Flask | [233] | ||
| (R)-pantothenate | Titer | 2.722 g/L * | 15.6 OD600* | Flask | [233] | ||
| (R)-pantothenate | Biomass-specific titer | 0.038 g/L/OD600 * | 18.57 OD600* | Flask | [233] | ||
| (R)-pantothenate | Biomass-specific titer | 0.172 g/L/OD600 * | 15.6 OD600* | Flask | [233] |
* Inferred from plots using RetroPlot.
Heterologous.
Target metabolites are shown in bold, while non-bold metabolites represent intermediates or potential byproducts.