anthranilate charts

Silencing

Overexpression

Feedback insensitive

Attenuation

Feed-forward insensitive

Inhibition insensitive

Unstated

Combined modifications

Titer in Fed-Batch for anthranilate

		Modifications
Strain	Maximum production	trpD_Ec	aroG_Ec	tktA_Ec	ptsH_Ec	ptsI_Ec	crr_Ec
E. coli W3110 trpD9923	4,210 mg/L
E. coli W3110 trpD9923PTS-/pv5Glk5GalP/pJLBaroG^fbrtktA	5,080 mg/L
E. coli W3110 trpD9923PTS^-/pv5Glk5GalP	5,300 mg/L
E. coli W3110 trpD9923/pJLBaroG^fbr	6,720 mg/L
E. coli W3110 trpD9923PTS^-/pJLBaroG^fbrtktA	7,160 mg/L
E. coli W3110 trpD9923 PTS^-	13,300 mg/L
E. coli W3110 trpD9923/pJLBaroG^fbrtktA	14,000 mg/L

Titer in Flask for anthranilate

		Modifications
Strain	Maximum production	trpD_Ec	ptsH_Ec	ptsI_Ec	crr_Ec	aroG_Ec	tktA_Ec
E. coli W3110 trpD9923	310 mg/L
E. coli W3110 trpD9923PTS^-/pv5Glk5GalP	330 mg/L
E. coli W3110 trpD9923PTS-/pv5Glk5GalP/pJLBaroG^fbrtktA	330 mg/L
E. coli W3110 trpD9923/pJLBaroG^fbr	440 mg/L
E. coli W3110 trpD9923PTS^-/pJLBaroG^fbrtktA	450 mg/L
E. coli W3110 trpD9923 PTS^-	700 mg/L
E. coli W3110 trpD9923/pJLBaroG^fbrtktA	750 mg/L

Substrate yield in Fed-Batch for anthranilate

		Modifications
Strain	Maximum production	trpD_Ec	aroG_Ec	tktA_Ec
E. coli W3110 trpD9923/pJLBaroG^fbrtktA	0.2 g/g of sustrate

Biomass-specific productivity in Fed-Batch for anthranilate

		Modifications
Strain	Maximum production	trpD_Ec	aroG_Ec	tktA_Ec
E. coli W3110 trpD9923/pJLBaroG^fbrtktA	20 mg/L/g DCW