Silencing
Overexpression
Feedback insensitive
Attenuation
Feed-forward insensitive
Inhibition insensitive
Unstated
Combined modifications

Titer in Fed-Batch for catechol

Modifications
Strain Maximum production trpDEc aroGEc tktAEc antAPa antBPa antCPa
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 4,470 mg/L

Titer in Flask for catechol

Modifications
Strain Maximum production trpDEc antAPa antBPa antCPa aroGEc tktAEc ptsHEc ptsIEc crrEc
E. coli W3110 trpD9923/pTrc-ant3 150 mg/L
E. coli trpD9923 PTS-/pTrc-ant3 370 mg/L
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 410 mg/L

Substrate yield in Fed-Batch for catechol

Modifications
Strain Maximum production trpDEc aroGEc tktAEc antAPa antBPa antCPa
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 0.16 g/g of sustrate

Substrate yield in Flask for catechol

Modifications
Strain Maximum production trpDEc ptsHEc ptsIEc crrEc antAPa antBPa antCPa aroGEc tktAEc
E. coli W3110 trpD9923/pTrc-ant3 0.05 g/g of sustrate
E. coli trpD9923 PTS-/pTrc-ant3 0.09 g/g of sustrate
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 0.1 g/g of sustrate

Biomass-specific productivity in Flask for catechol

Modifications
Strain Maximum production trpDEc ptsHEc ptsIEc crrEc antAPa antBPa antCPa aroGEc tktAEc
E. coli trpD9923 PTS-/pTrc-ant3 0.03 mg/L/g DCW
E. coli W3110 trpD9923/pTrc-ant3 50 mg/L/g DCW
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 70 mg/L/g DCW

Biomass-specific productivity in Fed-Batch for catechol

Modifications
Strain Maximum production trpDEc aroGEc tktAEc antAPa antBPa antCPa
E. coli W3110 trpD9923/pJLBaroGfbrtktA/pTrc-ant3 20 mg/L/g DCW