Silencing
Overexpression
Feedback insensitive
Attenuation
Feed-forward insensitive
Inhibition insensitive
Unstated
Combined modifications
Titer in Batch for (R)-lactate
| Modifications | ||||
|---|---|---|---|---|
| Strain | Maximum production | pflBEc | focAEc | adhEEc |
| E. coli SDU4 | 100,000 mg/L | |||
Titer in Fed-Batch for (R)-lactate
| Modifications | |||
|---|---|---|---|
| Strain | Maximum production | ptaEc | ppcEc |
| E. coli JP201 | 60,000 mg/L | ||
| E. coli JP203 | 62,200 mg/L | ||
Substrate yield in Batch for (R)-lactate
| Modifications | ||||
|---|---|---|---|---|
| Strain | Maximum production | pflBEc | focAEc | adhEEc |
| E. coli W3110 | 0.66251 g/g of sustrate | |||
| E. coli SDU2 | 0.82566 g/g of sustrate | |||
| E. coli SDU4 | 0.97398 g/g of sustrate | |||
Substrate yield in Flask for (R)-lactate
| Modifications | ||
|---|---|---|
| Strain | Maximum production | ptaEc |
| E. coli RR1 | 0.12855 g/g of sustrate | |
| E. coli JP201 | 0.7515 g/g of sustrate |
Substrate yield in Fed-Batch for (R)-lactate
| Modifications | |||
|---|---|---|---|
| Strain | Maximum production | ptaEc | ppcEc |
| E. coli JP203 | 0.9 g/g of sustrate | ||
Volumetric productivity in Fed-Batch for (R)-lactate
| Modifications | |||
|---|---|---|---|
| Strain | Maximum production | ptaEc | ppcEc |
| E. coli JP203 | 1,040 mg/L/h | ||
| E. coli JP201 | 1,090 mg/L/h | ||